DID YOU KNOW ''GLYCINE'' The Cheapest Anti-Aging Supplement That Actually Works
GLYCINE: The Cheapest Anti-Aging Supplement That Actually Works
.jpg)
What if feeling older, slower, or more tired wasn't just an inevitable part of aging, but a shortage of one small molecule your body depends on every single second?
That molecule is Glycine. While it’s the smallest amino acid in your body, it sits at the center of how you sleep, recover, and defend yourself from oxidative stress. Despite being overlooked by many, it is a foundational piece of your body’s master antioxidant system.
WATCH THE FULL VIDEO BELOW --👇👇👇👇
The Science of Glycine: More Than Just a Protein Builder
Glycine is involved in almost every biological process, from building proteins and forming collagen to supporting the liver and regulating neurotransmitters. However, its most critical role is in the production of Glutathione.
Glutathione is your body's "master antioxidant." It neutralizes reactive oxygen species—the tiny chemical sparks that damage DNA and cell membranes every time you produce energy. To make glutathione, your body needs three ingredients: glutamate, cysteine, and glycine. Often, glycine is the "rate-limiting factor," meaning if you run low, your entire detox and defense system slows down.
Better Sleep Through Chemistry
The strongest evidence for glycine supplementation is in the realm of sleep. Research suggests that taking glycine before bedtime can improve both subjective and objective sleep quality.
It works through a fascinating biological mechanism:
Core Cooling: Glycine activates receptors in the hypothalamus that relax your blood vessels. This allows heat to leave your body, dropping your core temperature—the natural signal your brain needs to fall asleep.
Quieting the Brain: It dials down "orexin" neurons, which are responsible for keeping you awake and alert during the day.
Muscle Recovery: Glycine helps muscles fully relax during REM sleep, ensuring your body can repair itself effectively throughout the night.
Glycine and Metabolism: A Conditional Necessity
While our bodies can technically make glycine, it may be "conditionally essential." This means that if you are dealing with metabolic syndrome, obesity, or insulin resistance, your body uses much more glycine than it can generate. Studies have shown that glycine levels are frequently lower in individuals with fatty liver disease or type 2 diabetes, suggesting that supplementation could help improve insulin sensitivity and reduce inflammation.
The "GlyNAC" Combination: The Ultimate Anti-Aging Duo?
You may have heard that you shouldn't take glycine alone, but rather as GlyNAC (Glycine + N-Acetylcysteine).
Because glutathione requires both glycine and cysteine, taking glycine alone is like having extra bricks but no cement. NAC delivers cysteine in a stable form. Recent 16-week randomized controlled trials in older adults showed that the GlyNAC combination improved:
Mitochondrial function and oxidative stress.
Muscle strength and walking speed.
Cognitive performance and insulin resistance.
How to Dose Glycine Safely
If you are young and healthy, glycine alone is likely enough, especially for sleep. However, if you are older or dealing with chronic inflammation, GlyNAC might be more effective.
For Sleep: The most studied dose is 3 grams taken 30 to 60 minutes before bed. It dissolves easily in water and has a pleasant, sweet taste.
For GlyNAC: Human studies typically use higher doses (around 7 grams of each for an average adult), but many people start at 3 grams of each per day to assess tolerance.
A Note on Mega-Dosing: While some studies on schizophrenia have used up to 60-90 grams a day, "mega-dosing" is generally not recommended for the general public due to potential risks of neurobehavioral changes or cardiovascular toxicity.
Potential Side Effects
Glycine is generally very well tolerated. At standard doses (3g), the most common side effect is mild sedation (which is often the goal). NAC can occasionally cause gastrointestinal issues like nausea or diarrhea.
As always, because everyone’s biology is unique, you should consult with your physician before adding these to your routine, especially if you have a history of asthma or are managing chronic health conditions.
Watch the full video below:
